Chloride intracellular channel (CLIC) proteins function as fusogens.
Bar Manori, Alisa Vaknin, Pavla Vaňková, Anat Nitzan, Ronen Zaidel-Bar, Petr Man, Moshe Giladi, Yoni Haitin
Full article at Nature communications
KU Leuven
Structural dynamics of the functional nonameric Type III translocase export gate
Full article at ScienceDirect
University of Bordeaux
The ion-coupling mechanism of human excitatory amino acid transporters
Full article at EMBOpress
National Research Council Canada
Epitope mapping of a blood–brain barrier crossing antibody targeting the cysteine-rich region of IGF1R using hydrogen-exchange mass spectrometry enabled by electrochemical reduction
Full article at Oxford Press
University of Ottawa
Arsenal of nanobodies shows broad-spectrum neutralization against SARS-CoV-2 variants of concern in vitro and in vivo in hamster models
Full article at Nature.com
University of Michigan, Ann Arbor
Trigger factor both holds and folds its client proteins
Full article at Nature
University of Cambridge
Structural basis of rotavirus RNA chaperone displacement and RNA annealing
Full article at PNAS
University of Leeds
Pocket delipidation induced by membrane tension or modification leads to a structurally analogous mechanosensitive channel state
Full article at Science Direct
AXON Neuroscience R&D Services SE
Monoclonal antibodies targeting two immunodominant epitopes on the Spike protein neutralize emerging SARS-CoV-2 variants of concern
Full article at Science Direct
Universidad Autonoma de San Luis Potos
Cryptic in vitro ubiquitin ligase activity of HDMX towards p53 is probably regulated by an induced fit mechanism
Full article at Portland Press
Institut Pasteur
De novo sequencing of antibody light chain proteoforms from patients with multiple myeloma
Full article at ACS
Masaryk University, Brno
Hydrogen deuterium exchange mass spectrometry identifies the dominant paratope in CD20 antigen binding to the NCD1.2 monoclonal antibody
Full article at Portland Press
Institut Pasteur
De Novo Sequencing of Antibody Light Chain Proteoforms from Patients with Multiple Myeloma
Full article at ACS
University of Dundee
Mapping of a N-terminal α-helix domain required for human PINK1 stabilization, Serine228 autophosphorylation and activation in cells
Full article at Open Biology
Centre National de la Recherche Scientifique, Illkirch
Cytosolic sequestration of the vitamin D receptor as a therapeutic option for vitamin D-induced hypercalcemia
Full article at Nature
University of Cambridge
Structural basis of rotavirus RNA chaperone displacement and RNA annealing
Full article at PNAS
The Hebrew University of Jerusalem
Defining Hsp33’s Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry
Full article at jove.com
University of Leeds
Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients
Full article at Nature